Bioscience Vaccines is an early
stage life science company commercializing a novel adjuvant technology to
improve the safety and effectiveness of vaccine products.
Bioscience Vaccines’ proprietary Matrix ImmuneModulator™
uses an FDA approved technology
currently marketed for medical device applications. In the last 10 years, the Matrix Immune Modulator material has been safely used in over 2 million patientswithout product recalls or
adverse side effects. Testing in bench and animal models has shown that, when
used as an adjuvant, Bioscience Vaccines’ Matrix Immune Modulator
can substantially increase the effectiveness of vaccines.
Bioscience
Vaccines’ Matrix Immune Modulator technology is based on an abundant, naturally
occurring biomaterial that is cost efficient to produce. The Matrix Immune
Modulator boosts the immune response to
vaccines consequently decreasing the required amount of the active component
(antigen) that is required in each vaccination. As the U.S. President's Council
of Advisors on Science and Technology (PCAST) recognizes, “the number of doses
of killed virus vaccine can be increased two- to ten-fold when an adjuvanted
vaccine is used.” By using Matrix Immune Modulator
as an adjuvant, the availability of vaccines will
increase and the cost of each inoculation will decrease.
Matrix
Immune Modulator offers a superior adjuvant to other technologies. The Matrix
Immune Modulator:
·
Is robust and shelf stable for at least 18 months without refrigeration
· Is not limited to specific classes of antigens or immune responses
· Is effective without a need to combine it with other materials
· Does not result in local (injection site) reactions · Currently available in 3 different formulations (MIM90, MIM150, and MIM250)
· Can be produced easily in a cost efficient manner
The need for increased vaccine production is a combination of three
primary drivers:
·
Global
mobilization of populations accerlating the spread of contagious diseases
higher rates · Threats of attacks on populations using bio-warfare leaving civilizations at risk · The awareness and
concern of public health problems in emerging and developing countries.
New vaccines are
emerging that have the potential to be billion-dollar product lines as
stand-alone products. The prophylactic vaccine market was $22 billion in 2009 and estimated to increase at a compound annual rate of 9.7% over the next 5 years (Kolorama, 2010). The forecasted annual market revenue for vaccine adjuvant products like Bioscience Vaccines, Inc.'s MIM is estimated to be in excess of $2 billion. With proof-of-concept testing and advanced manufacturing agreements finalized, Bioscience Vaccines, Inc. is well positioned to be a provider of this key component for both existing and emerging vaccine markets.
Optimization of our MIM technology for use in vaccine products targeting infectious diseases and biodefense.
Establish and build commercial leverage through partnering and sublicensing with strategic partners.